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Can Gleevec cure gist? Currently, three drugs are commonly used in adjuvant and neoadjuvant therapy to treat GIST. Gleevec (imatinib) is the 'first-line' therapy for the treatment of GIST. It can be used to shrink a tumor prior to surgery, and also after surgery to prevent or delay a recurrence in cases of high-risk GIST. fo7gxxv7wh
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